Sao Paolo is not itself a cruise port, but is served by the port of Santos. Combined, the port of Santos serves as the departure port for approximately fifty-five annual sailings from both Costa and MSC to South America, as well as other places.
Sailings leaving from Sao Paolo during the the peak season of winter are much more expensive than the the low season of spring. Overall Sao Paolo is somewhat inexpensive compared to other ports. The illustration below shows the monthly average cost per day for cruises from Sao Paolo (Cruises only depart from Sao Paolo between December and November).
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