Sao Paolo is not a cruise port, but is served by the port of Santos. In total, the cruise port of Santos serves as the departure port for around fifty cruises yearly from both Costa and MSC to South America.
On average Sao Paolo is extremely affordable compared to other ports. The graph below shows the monthly average cost per day for cruises from Sao Paolo (Cruises only depart from Sao Paolo between January and December). Sailings scheduled from Sao Paolo during the peak seasons of winter and fall are significantly more expensive than the the low season of spring.