11 Night from San Diego to Panama City on the Crystal Serenity
Settle in for eleven nights of exciting travel around the Caribbean when you embark on the Crystal Serenity from San Diego to Panama City.
Stopping in very uncommon cities such as San Juan del Sur, Zihuatanejo, and Manzanillo makes this cruise particularly exciting. This route is an uncommon one for the Serenity, As it sails it only once.
The price includes all meals, entertainment, taxes, and fees. No sneaky extra fees!
The Crystal Serenity
The Serenity Crystal is the flagship of the class, based in Europe, that can house comfortably over 700 guests.
The Serenity Crystal offers guests a casino, a ping pong table, a gym, a spa, and a jacuzzi.
Your Itinerary
This cruise spends six days in port and four days at sea. Highlights include a long stop in Manzanillo plus visits to rare stops like San Juan del Sur and Zihuatanejo.
| Date | Port | Arrive | Depart |
|---|---|---|---|
| Mon, Aug 9 | San Diego, CA | 7:00pm | |
| Tue, Aug 10 | At Sea | ||
| Wed, Aug 11 | At Sea | ||
| Thu, Aug 12 | Puerto Vallarta, Mexico | 9:00am | 6:00pm |
| Fri, Aug 13 | Manzanillo, Mexico | 7:00am | 6:00pm |
| Sat, Aug 14 | Zihuatanejo, Mexico | 7:00am | 3:00pm |
| Sun, Aug 15 | At Sea | ||
| Mon, Aug 16 | Acajutla, El Salvador | 8:00am | 5:00pm |
| Tue, Aug 17 | San Juan del Sur, Nicaragua | 10:00am | 6:00pm |
| Wed, Aug 18 | Puntarenas, Costa Rica | 7:00am | 5:00pm |
| Thu, Aug 19 | At Sea | ||
| Fri, Aug 20 | Fuerte Amador, Panama (Panama City) | 7:00am |
Alternate Sailings
The Serenity sails this route once next year, but doesn't sail it this year. No other ship sails this exact same route. In the accompanying graphic you can see a visualization of when this ship sails as well as the relative price for an outside cabin.
Book Your Cruise
Since being listed 1 days ago, the price of this sailing has remained right at $5,030 for an outside cabin. The accompanying graph shows the price over time for every type of cabin. Right now this cruise is at its lowest price, so lock in your outside room now before it goes up.
Last Updated: Jul 18, 2026
Last Modified: Jul 17, 2026