Cruises From Colon, Panama
51 cruises depart from Colon in 2026–2028, with fares from $547 per person. Cruise lines sailing from Colon include Royal Caribbean and Crystal. Popular destinations include Cartagena, Colombia, Oranjestad, Willemstad, Kralendijk, Santa Marta, and Port of Spain. Sailing soon? See last minute cruises from Colon. For terminal info, parking, and things to do ashore, see our Colon Cruise Port Guide.
Frequently Asked Questions about Cruises from Colon
❓ How many cruises depart from Colon?
51 cruises depart from Colon, sailing in 2026-2028.
❓ How much does a cruise from Colon cost?
Fares start at $547 per person; the total depends on the cruise line, cabin, and season.
❓ What cruise lines leave from Colon?
Cruise lines sailing out of Colon include Royal Caribbean and Crystal.
❓ How long are cruises from Colon?
Cruises out of Colon range from 7 to 14 nights, with 7-night sailings the most common.
❓ Where do cruises from Colon go?
Popular destinations from Colon include Cartagena, Colombia, Oranjestad, Willemstad, Kralendijk, Santa Marta, and Port of Spain.
