Colon

Cruises From Colon

Cruises From Colon, Panama

42 cruises depart from Colon in 2026–2028, with fares from $846 per person. Cruise lines sailing from Colon include Royal Caribbean and Crystal. Popular destinations include Cartagena, Colombia, Oranjestad, Willemstad, Kralendijk, Santa Marta, and Port of Spain. Sailing soon? See last minute cruises from Colon. For terminal info, parking, and things to do ashore, see our Colon Cruise Port Guide.

LOWEST PRICE EVER
November 14, 2026
10 Night Southern Caribbean Cruise
CruiseScore™ (4.33/5)
Royal Caribbean Grandeur of the Seas
S M L XL
Colon → Kralendijk → Oranjestad → Willemstad → Port of Spain → Scarborough → Colon
$1,271
$127 per day
Inside
March 6, 2027
7 Night Southern Caribbean Cruise
CruiseScore™ (4.42/5)
Royal Caribbean Grandeur of the Seas
S M L XL
Colon → Cartagena, Colombia → Oranjestad → Willemstad → Colon
$919
$131 per day
Outside
April 24, 2027
Royal Caribbean Grandeur of the Seas
S M L XL
Colon → Bequia → Castries → St. John's, Antigua → Tortola → San Juan
$865
$124 per day
Outside
LOWEST PRICE EVER
January 29, 2028
Royal Caribbean Grandeur of the Seas
S M L XL
Colon → Cartagena, Colombia → Oranjestad → Willemstad → Colon
$846
$121 per day
Inside
February 19, 2028
Royal Caribbean Grandeur of the Seas
S M L XL
Colon → Cartagena, Colombia → Willemstad → Oranjestad → Colon
$888
$127 per day
Inside
LOWEST PRICE EVER
January 1, 2028
Royal Caribbean Grandeur of the Seas
S M L XL
Colon → Cartagena, Colombia → Willemstad → Oranjestad → Colon
$896
$128 per day
Inside
February 5, 2028
Royal Caribbean Grandeur of the Seas
S M L XL
Colon → Cartagena, Colombia → Oranjestad → Willemstad → Colon
$967
$138 per day
Outside
January 22, 2028
Royal Caribbean Grandeur of the Seas
S M L XL
Colon → Cartagena, Colombia → Willemstad → Oranjestad → Colon
$916
$131 per day
Inside
February 13, 2027
7 Night Southern Caribbean Cruise
CruiseScore™ (4.28/5)
Royal Caribbean Grandeur of the Seas
S M L XL
Colon → Cartagena, Colombia → Oranjestad → Kralendijk → Colon
$1,055
$151 per day
Outside
February 26, 2028
Royal Caribbean Grandeur of the Seas
S M L XL
Colon → Cartagena, Colombia → Willemstad → Oranjestad → Colon
$919
$131 per day
Inside
January 15, 2028
Royal Caribbean Grandeur of the Seas
S M L XL
Colon → Cartagena, Colombia → Willemstad → Oranjestad → Colon
$978
$140 per day
Outside
February 27, 2027
7 Night Southern Caribbean Cruise
CruiseScore™ (4.36/5)
Royal Caribbean Grandeur of the Seas
S M L XL
Colon → Cartagena, Colombia → Oranjestad → Willemstad → Colon
$989
$141 per day
Inside
January 8, 2028
Royal Caribbean Grandeur of the Seas
S M L XL
Colon → Cartagena, Colombia → Oranjestad → Willemstad → Colon
$938
$134 per day
Inside
March 25, 2028
Royal Caribbean Grandeur of the Seas
S M L XL
Colon → Cartagena, Colombia → Oranjestad → Willemstad → Colon
$946
$135 per day
Inside
March 18, 2028
Royal Caribbean Grandeur of the Seas
S M L XL
Colon → Cartagena, Colombia → Willemstad → Oranjestad → Colon
$946
$135 per day
Inside

Frequently Asked Questions about Cruises from Colon

❓ How many cruises depart from Colon?

42 cruises depart from Colon, sailing in 2026-2028.

❓ How much does a cruise from Colon cost?

Fares start at $846 per person; the total depends on the cruise line, cabin, and season.

❓ What cruise lines leave from Colon?

Cruise lines sailing out of Colon include Royal Caribbean and Crystal.

❓ How long are cruises from Colon?

Cruises out of Colon range from 7 to 14 nights, with 7-night sailings the most common.

❓ Where do cruises from Colon go?

Popular destinations from Colon include Cartagena, Colombia, Oranjestad, Willemstad, Kralendijk, Santa Marta, and Port of Spain.

Get Weekly Cruise Deals

Weekly emails with the best deals, fully customized for you. No spam ever.

Let’s book your cruise

Tell us who’s sailing to see available cabins and fares.

Guests in this cabin
Ages at the time of sailing

Special fares are dependent on eligibility