Colon

Cruises From Colon

Cruises From Colon, Panama

45 cruises depart from Colon in 2026–2028, with fares from $672 per person. Cruise lines sailing from Colon include Royal Caribbean and Crystal. Popular destinations include Cartagena, Colombia, Oranjestad, Willemstad, Kralendijk, Santa Marta, and Port of Spain. Sailing soon? See last minute cruises from Colon. For terminal info, parking, and things to do ashore, see our Colon Cruise Port Guide.

April 24, 2027
Royal Caribbean Grandeur of the Seas
S M L XL
Colon → Bequia → Castries → St. John's, Antigua → Tortola → San Juan
$672
$96 per day
Inside
November 14, 2026
10 Night Southern Caribbean Cruise
CruiseScore™ (4.28/5)
Royal Caribbean Grandeur of the Seas
S M L XL
Colon → Kralendijk → Oranjestad → Willemstad → Port of Spain → Scarborough → Colon
$1,259
$126 per day
Outside
March 6, 2027
7 Night Southern Caribbean Cruise
CruiseScore™ (4.47/5)
Royal Caribbean Grandeur of the Seas
S M L XL
Colon → Cartagena, Colombia → Oranjestad → Willemstad → Colon
$1,313
$188 per day
Suite
February 19, 2028
Royal Caribbean Grandeur of the Seas
S M L XL
Colon → Cartagena, Colombia → Willemstad → Oranjestad → Colon
$888
$127 per day
Inside
February 5, 2028
Royal Caribbean Grandeur of the Seas
S M L XL
Colon → Cartagena, Colombia → Oranjestad → Willemstad → Colon
$967
$138 per day
Outside
January 29, 2028
Royal Caribbean Grandeur of the Seas
S M L XL
Colon → Cartagena, Colombia → Oranjestad → Willemstad → Colon
$919
$131 per day
Inside
February 26, 2028
Royal Caribbean Grandeur of the Seas
S M L XL
Colon → Cartagena, Colombia → Willemstad → Oranjestad → Colon
$919
$131 per day
Inside
October 24, 2026
7 Night Southern Caribbean Cruise
CruiseScore™ (4.13/5)
Royal Caribbean Grandeur of the Seas
S M L XL
Colon → Cartagena, Colombia → Oranjestad → Willemstad → Colon
$1,511
$216 per day
Suite
PRICE DROP
March 13, 2027
7 Night Southern Caribbean Cruise
CruiseScore™ (4.33/5)
Royal Caribbean Grandeur of the Seas
S M L XL
Colon → Cartagena, Colombia → Willemstad → Kralendijk → Oranjestad → Colon
$1,016
$145 per day
Inside
March 27, 2027
7 Night Southern Caribbean Cruise
CruiseScore™ (4.23/5)
Royal Caribbean Grandeur of the Seas
S M L XL
Colon → Cartagena, Colombia → Willemstad → Kralendijk → Oranjestad → Colon
$1,016
$145 per day
Inside
January 15, 2028
Royal Caribbean Grandeur of the Seas
S M L XL
Colon → Cartagena, Colombia → Willemstad → Oranjestad → Colon
$1,009
$144 per day
Outside
December 11, 2027
Royal Caribbean Grandeur of the Seas
S M L XL
Colon → Cartagena, Colombia → Oranjestad → Willemstad → Colon
$969
$138 per day
Inside
March 4, 2028
Royal Caribbean Grandeur of the Seas
S M L XL
Colon → Cartagena, Colombia → Willemstad → Oranjestad → Colon
$966
$138 per day
Inside
March 18, 2028
Royal Caribbean Grandeur of the Seas
S M L XL
Colon → Cartagena, Colombia → Willemstad → Oranjestad → Colon
$966
$138 per day
Inside
January 1, 2028
Royal Caribbean Grandeur of the Seas
S M L XL
Colon → Cartagena, Colombia → Willemstad → Oranjestad → Colon
$966
$138 per day
Inside

Frequently Asked Questions about Cruises from Colon

❓ How many cruises depart from Colon?

45 cruises depart from Colon, sailing in 2026-2028.

❓ How much does a cruise from Colon cost?

Fares start at $672 per person; the total depends on the cruise line, cabin, and season.

❓ What cruise lines leave from Colon?

Cruise lines sailing out of Colon include Royal Caribbean and Crystal.

❓ How long are cruises from Colon?

Cruises out of Colon range from 7 to 14 nights, with 7-night sailings the most common.

❓ Where do cruises from Colon go?

Popular destinations from Colon include Cartagena, Colombia, Oranjestad, Willemstad, Kralendijk, Santa Marta, and Port of Spain.

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