Cruises From Palermo, Sicily
277 cruises depart from Palermo in 2026–2028, with fares from $298 per person. Cruise lines sailing from Palermo include MSC and Costa. Popular destinations include Marseille, Barcelona, Portofino, Naples, Tunis, and Civitavecchia. Sailing soon? See last minute cruises from Palermo. For terminal info, parking, and things to do ashore, see our Palermo Cruise Port Guide.
LOWEST PRICE EVER
September 16, 2026
4 Night Western Mediterranean from Palermo Cruise
CruiseScore™ (3.99/5)
Costa Fascinosa
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M
L
XL
Palermo
→
Naples
→
Rome
→
Ajaccio
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Savona
Inside
Inside
November 26, 2026
7 Night Round Trip European Cruise from Palermo
CruiseScore™ (3.87/5)
Costa Toscana
S
M
L
XL
Palermo
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Rome
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Savona
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Marseille
→
Barcelona
→
Palma de Mallorca
→
Palermo
Inside
Inside
December 10, 2026
7 Night Round Trip European Cruise from Palermo
CruiseScore™ (3.87/5)
Costa Toscana
S
M
L
XL
Palermo
→
Rome
→
Savona
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Marseille
→
Barcelona
→
Palma de Mallorca
→
Palermo
Inside
Inside
December 3, 2026
7 Night Round Trip European Cruise from Palermo
CruiseScore™ (3.87/5)
Costa Toscana
S
M
L
XL
Palermo
→
Rome
→
Savona
→
Marseille
→
Barcelona
→
Palma de Mallorca
→
Palermo
Inside
Inside
January 27, 2027
7 Night Mediterranean Cruise
CruiseScore™ (3.99/5)
MSC Euribia
S
M
L
XL
Palermo
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Tunis
→
Barcelona
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Marseille
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Portofino
→
Naples
→
Palermo
Inside
Inside
January 7, 2027
7 Night Western Mediterranean from Palermo Cruise
CruiseScore™ (3.87/5)
Costa Toscana
S
M
L
XL
Palermo
→
Rome
→
Savona
→
Marseille
→
Barcelona
→
Palma de Mallorca
→
Palermo
Inside
Inside
LOWEST PRICE EVER
March 17, 2027
7 Night Mediterranean Cruise
CruiseScore™ (3.99/5)
MSC Euribia
S
M
L
XL
Palermo
→
Tunis
→
Barcelona
→
Marseille
→
Portofino
→
Naples
→
Palermo
Inside
Inside
November 5, 2026
7 Night Mediterranean Cruise
CruiseScore™ (4.02/5)
MSC Splendida
S
M
L
XL
Palermo
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Valletta
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Barcelona
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Marseille
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Florence
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Cagliari
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Palermo
Outside
Outside
January 14, 2027
7 Night Western Mediterranean from Palermo Cruise
CruiseScore™ (3.87/5)
Costa Toscana
S
M
L
XL
Palermo
→
Rome
→
Savona
→
Marseille
→
Barcelona
→
Palma de Mallorca
→
Palermo
Inside
Inside
January 21, 2027
7 Night Western Mediterranean from Palermo Cruise
CruiseScore™ (3.87/5)
Costa Toscana
S
M
L
XL
Palermo
→
Rome
→
Savona
→
Marseille
→
Barcelona
→
Palma de Mallorca
→
Palermo
Inside
Inside
January 28, 2027
7 Night Western Mediterranean from Palermo Cruise
CruiseScore™ (3.87/5)
Costa Toscana
S
M
L
XL
Palermo
→
Rome
→
Savona
→
Marseille
→
Barcelona
→
Palma de Mallorca
→
Palermo
Inside
Inside
February 17, 2027
7 Night Mediterranean Cruise
CruiseScore™ (3.99/5)
MSC Euribia
S
M
L
XL
Palermo
→
Tunis
→
Barcelona
→
Marseille
→
Portofino
→
Naples
→
Palermo
Inside
Inside
February 10, 2027
7 Night Mediterranean Cruise
CruiseScore™ (3.99/5)
MSC Euribia
S
M
L
XL
Palermo
→
Tunis
→
Barcelona
→
Marseille
→
Portofino
→
Naples
→
Palermo
Outside
Outside
February 3, 2027
7 Night Mediterranean Cruise
CruiseScore™ (3.99/5)
MSC Euribia
S
M
L
XL
Palermo
→
Tunis
→
Barcelona
→
Marseille
→
Portofino
→
Naples
→
Palermo
Outside
Outside
January 6, 2027
7 Night Mediterranean Cruise
CruiseScore™ (3.99/5)
MSC Euribia
S
M
L
XL
Palermo
→
Tunis
→
Barcelona
→
Marseille
→
Portofino
→
Naples
→
Palermo
Outside
Outside
Frequently Asked Questions about Cruises from Palermo
❓ How many cruises depart from Palermo?
277 cruises depart from Palermo, sailing in 2026-2028.
❓ How much does a cruise from Palermo cost?
Fares start at $298 per person; the total depends on the cruise line, cabin, and season.
❓ What cruise lines leave from Palermo?
Cruise lines sailing out of Palermo include MSC and Costa.
❓ How long are cruises from Palermo?
Cruises out of Palermo range from 3 to 7 nights, with 7-night sailings the most common.
❓ Where do cruises from Palermo go?
Popular destinations from Palermo include Marseille, Barcelona, Portofino, Naples, Tunis, and Civitavecchia.
