Cruises From Portofino, Italy
543 cruises depart from Portofino in 2026–2028, with fares from $297 per person. Cruise lines sailing from Portofino include MSC, Costa, and Seabourn. Popular destinations include Marseille, Barcelona, Civitavecchia, Naples, Palermo, and Valletta. Sailing soon? See last minute cruises from Portofino. For terminal info, parking, and things to do ashore, see our Portofino Cruise Port Guide.
LOWEST PRICE EVER
October 30, 2026
7 Night Western Mediterranean & Genova Cruise
CruiseScore™ (3.98/5)
Costa Toscana
S
M
L
XL
Portofino
→
Marseille
→
Barcelona
→
Cagliari
→
Naples
→
Rome
→
Portofino
Balcony
LOWEST PRICE EVER
November 15, 2026
7 Night Mediterranean Cruise
CruiseScore™ (3.75/5)
MSC Magnifica
S
M
L
XL
Portofino
→
Naples
→
Messina
→
Valletta
→
Barcelona
→
Marseille
→
Portofino
Inside
LOWEST PRICE EVER
October 30, 2026
17 Night Westbound Transatlantic Cruise from Portofino to La Romana
CruiseScore™ (3.69/5)
MSC Opera
S
M
L
XL
Portofino
→
Florence
→
Marseille
→
Barcelona
→
Tangier
→
St. John's, Antigua
→
Philipsburg
→
Basse-Terre
→
La Romana
Outside
LOWEST PRICE EVER
November 29, 2026
7 Night Mediterranean Cruise
CruiseScore™ (3.75/5)
MSC Magnifica
S
M
L
XL
Portofino
→
Naples
→
Messina
→
Valletta
→
Barcelona
→
Marseille
→
Portofino
Inside
LOWEST PRICE EVER
November 6, 2026
7 Night Western Mediterranean & Genova Cruise
CruiseScore™ (3.90/5)
Costa Toscana
S
M
L
XL
Portofino
→
Marseille
→
Barcelona
→
Palma de Mallorca
→
Naples
→
Rome
→
Portofino
Inside
LOWEST PRICE EVER
October 26, 2026
18 Night Grand Voyages Cruise
CruiseScore™ (4.24/5)
MSC Grandiosa
S
M
L
XL
Portofino
→
Florence
→
Rome
→
Palma de Mallorca
→
Barcelona
→
Funchal
→
San Juan
→
Miami
Outside
October 16, 2026
7 Night Western Mediterranean & Genova Cruise
CruiseScore™ (4.12/5)
Costa Toscana
S
M
L
XL
Portofino
→
Marseille
→
Barcelona
→
Cagliari
→
Naples
→
Rome
→
Portofino
Outside
November 8, 2026
7 Night Mediterranean Cruise
CruiseScore™ (3.83/5)
MSC Magnifica
S
M
L
XL
Portofino
→
Naples
→
Messina
→
Valletta
→
Barcelona
→
Marseille
→
Portofino
Inside
LOWEST PRICE EVER
December 8, 2026
7 Night Mediterranean Cruise
CruiseScore™ (3.56/5)
MSC Sinfonia
S
M
L
XL
Portofino
→
Florence
→
Rome
→
Valencia
→
Barcelona
→
Marseille
→
Portofino
Inside
LOWEST PRICE EVER
November 22, 2026
7 Night Mediterranean Cruise
CruiseScore™ (3.75/5)
MSC Magnifica
S
M
L
XL
Portofino
→
Naples
→
Messina
→
Valletta
→
Barcelona
→
Marseille
→
Portofino
Inside
LOWEST PRICE EVER
December 1, 2026
7 Night Mediterranean Cruise
CruiseScore™ (3.56/5)
MSC Sinfonia
S
M
L
XL
Portofino
→
Florence
→
Rome
→
Valencia
→
Barcelona
→
Marseille
→
Portofino
Inside
October 23, 2026
7 Night Western Mediterranean & Genova Cruise
CruiseScore™ (4.12/5)
Costa Toscana
S
M
L
XL
Portofino
→
Marseille
→
Barcelona
→
Cagliari
→
Naples
→
Rome
→
Portofino
Balcony
LOWEST PRICE EVER
October 2, 2026
7 Night Western Mediterranean & Genova Cruise
CruiseScore™ (4.12/5)
Costa Toscana
S
M
L
XL
Portofino
→
Marseille
→
Barcelona
→
Cagliari
→
Naples
→
Rome
→
Portofino
Outside
LOWEST PRICE EVER
October 26, 2026
19 Night Grand Voyage
CruiseScore™ (4.34/5)
MSC Grandiosa
S
M
L
XL
Portofino
→
Florence
→
Rome
→
Palma de Mallorca
→
Barcelona
→
Funchal
→
San Juan
→
Miami
→
Port Canaveral
Outside
LOWEST PRICE EVER
October 31, 2026
16 Night MSC Grand Voyages
CruiseScore™ (4.08/5)
MSC Divina
S
M
L
XL
Portofino
→
Tarragona
→
Tenerife
→
Salvador
→
Rio de Janeiro
→
Sao Paulo
Inside
Frequently Asked Questions about Cruises from Portofino
❓ How many cruises depart from Portofino?
543 cruises depart from Portofino, sailing in 2026-2028.
❓ How much does a cruise from Portofino cost?
Fares start at $297 per person; the total depends on the cruise line, cabin, and season.
❓ What cruise lines leave from Portofino?
Cruise lines sailing out of Portofino include MSC, Costa, and Seabourn.
❓ How long are cruises from Portofino?
Cruises out of Portofino range from 1 to 28 nights, with 7-night sailings the most common.
❓ Where do cruises from Portofino go?
Popular destinations from Portofino include Marseille, Barcelona, Civitavecchia, Naples, Palermo, and Valletta.
