Portofino

Cruises From Portofino

Cruises From Portofino, Italy

594 cruises depart from Portofino in 2026–2028, with fares from $79 per person. Cruise lines sailing from Portofino include MSC, Costa, and Seabourn. Popular destinations include Marseille, Barcelona, Civitavecchia, Naples, Palermo, and Valletta. Sailing soon? See last minute cruises from Portofino. For terminal info, parking, and things to do ashore, see our Portofino Cruise Port Guide.

18 Night Portofino to Miami cruise
October 26, 2026
18 Night Grand Voyages Cruise
CruiseScore™ (4.21/5)
MSC Grandiosa
S M L XL
Portofino → Florence → Rome → Palma Mallorca → Barcelona → Funchal → San Juan → Miami
$728
$40 per day
Inside
LOWEST PRICE EVER
17 Night Portofino to La Romana cruise
October 30, 2026
17 Night Grand Voyages Cruise
CruiseScore™ (3.65/5)
MSC Opera
S M L XL
Portofino → Florence → Marseille → Barcelona → Tangier → St. John's → St. Maarten → Basse-Terre → La Romana
$700
$41 per day
Inside
7 Night Portofino to Portofino cruise
December 1, 2026
7 Night Mediterranean Cruise
CruiseScore™ (3.56/5)
MSC Sinfonia
S M L XL
Portofino → Florence → Rome → Valencia → Barcelona → Marseille → Portofino
$501
$72 per day
Inside
LOWEST PRICE EVER
7 Night Portofino to Portofino cruise
December 8, 2026
7 Night Mediterranean Cruise
CruiseScore™ (3.56/5)
MSC Sinfonia
S M L XL
Portofino → Florence → Rome → Valencia → Barcelona → Marseille → Portofino
$481
$69 per day
Inside
LOWEST PRICE EVER
7 Night Portofino to Portofino cruise
December 15, 2026
7 Night Mediterranean Cruise
CruiseScore™ (3.56/5)
MSC Sinfonia
S M L XL
Portofino → Florence → Rome → Valencia → Barcelona → Marseille → Portofino
$481
$69 per day
Inside
LOWEST PRICE EVER
7 Night Portofino to Portofino cruise
December 7, 2026
7 Night Mediterranean Cruise
CruiseScore™ (4.06/5)
MSC Euribia
S M L XL
Portofino → Naples → Palermo → Tunis → Barcelona → Marseille → Portofino
$501
$72 per day
Inside
7 Night Portofino to Portofino cruise
November 24, 2026
7 Night Mediterranean Cruise
CruiseScore™ (3.56/5)
MSC Sinfonia
S M L XL
Portofino → Florence → Rome → Valencia → Barcelona → Marseille → Portofino
$521
$74 per day
Inside
19 Night Portofino to Port Canaveral cruise
October 26, 2026
19 Night Grand Voyage
CruiseScore™ (4.34/5)
MSC Grandiosa
S M L XL
Portofino → Florence → Rome → Palma Mallorca → Barcelona → Funchal → San Juan → Miami → Port Canaveral
$1,259
$66 per day
Outside
4 Night Portofino to Valencia cruise
January 12, 2027
4 Night Mediterranean Cruise
CruiseScore™ (3.51/5)
MSC Sinfonia
S M L XL
Portofino → Florence → Rome → Valencia
$239
$60 per day
Inside
LOWEST PRICE EVER
7 Night Portofino to Portofino cruise
November 8, 2026
7 Night Mediterranean Cruise
CruiseScore™ (3.75/5)
MSC Magnifica
S M L XL
Portofino → Naples → Messina → Valletta → Barcelona → Marseille → Portofino
$601
$86 per day
Outside
PRICE RISING
7 Night Portofino to Portofino cruise
October 30, 2026
Costa Toscana
S M L XL
Portofino → Marseille → Barcelona → Cagliari → Naples → Rome → Portofino
$670
$96 per day
Inside
PRICE RISING
7 Night Portofino to Portofino cruise
October 23, 2026
Costa Toscana
S M L XL
Portofino → Marseille → Barcelona → Cagliari → Naples → Rome → Portofino
$670
$96 per day
Inside
LOWEST PRICE EVER
7 Night Portofino to Portofino cruise
November 10, 2026
7 Night Mediterranean Cruise
CruiseScore™ (3.56/5)
MSC Sinfonia
S M L XL
Portofino → Florence → Rome → Valencia → Barcelona → Marseille → Portofino
$571
$82 per day
Inside
LOWEST PRICE EVER
7 Night Portofino to Portofino cruise
November 6, 2026
Costa Toscana
S M L XL
Portofino → Marseille → Barcelona → Palma Mallorca → Naples → Rome → Portofino
$688
$98 per day
Inside
16 Night Portofino to Sao Paolo cruise
October 31, 2026
16 Night MSC Grand Voyages
CruiseScore™ (4.08/5)
MSC Divina
S M L XL
Portofino → Tarragona → Tenerife → Salvador → Rio → Sao Paolo
$1,098
$69 per day
Inside

Frequently Asked Questions about Cruises from Portofino

❓ How many cruises depart from Portofino?

594 cruises depart from Portofino, sailing in 2026-2028.

❓ How much does a cruise from Portofino cost?

Fares start at $79 per person; the total depends on the cruise line, cabin, and season.

❓ What cruise lines leave from Portofino?

Cruise lines sailing out of Portofino include MSC, Costa, and Seabourn.

❓ How long are cruises from Portofino?

Cruises out of Portofino range from 1 to 28 nights, with 7-night sailings the most common.

❓ Where do cruises from Portofino go?

Popular destinations from Portofino include Marseille, Barcelona, Civitavecchia, Naples, Palermo, and Valletta.

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