Santo Domingo

Cruises From Santo Domingo

Cruises From Santo Domingo, Dominican Republic

32 cruises depart from Santo Domingo in 2026–2028, with fares from $499 per person. Cruise lines sailing from Santo Domingo include Costa. Popular destinations include Pointe-a-Pitre, Fort-de-France, Basseterre, St. John's, Antigua, Tortola, and Philipsburg. Sailing soon? See last minute cruises from Santo Domingo. For terminal info, parking, and things to do ashore, see our Santo Domingo Cruise Port Guide.

LOWEST PRICE EVER
December 14, 2026
Costa Favolosa
S M L XL
Santo Domingo → Fort-de-France → Pointe-a-Pitre → Basseterre → St. John's, Antigua → Tortola → Santo Domingo
$499
$71 per day
Inside
LOWEST PRICE EVER
December 21, 2026
Costa Favolosa
S M L XL
Santo Domingo → Fort-de-France → Pointe-a-Pitre → Philipsburg → Basseterre → Tortola → Santo Domingo
$598
$85 per day
Inside
LOWEST PRICE EVER
February 8, 2027
Costa Favolosa
S M L XL
Santo Domingo → St. John's, Antigua → Fort-de-France → Pointe-a-Pitre → Basseterre → Tortola → Santo Domingo
$549
$78 per day
Inside
LOWEST PRICE EVER
February 15, 2027
Costa Favolosa
S M L XL
Santo Domingo → St. John's, Antigua → Fort-de-France → Pointe-a-Pitre → Basseterre → Tortola → Santo Domingo
$549
$78 per day
Inside
LOWEST PRICE EVER
January 11, 2027
Costa Favolosa
S M L XL
Santo Domingo → Philipsburg → Fort-de-France → Pointe-a-Pitre → Basseterre → Tortola → Santo Domingo
$529
$76 per day
Inside
LOWEST PRICE EVER
January 18, 2027
Costa Favolosa
S M L XL
Santo Domingo → St. John's, Antigua → Fort-de-France → Pointe-a-Pitre → Basseterre → Philipsburg → Santo Domingo
$529
$76 per day
Inside
LOWEST PRICE EVER
January 4, 2027
Costa Favolosa
S M L XL
Santo Domingo → St. John's, Antigua → Fort-de-France → Pointe-a-Pitre → Basseterre → Tortola → Santo Domingo
$589
$84 per day
Inside
LOWEST PRICE EVER
January 25, 2027
Costa Favolosa
S M L XL
Santo Domingo → Roseau → Fort-de-France → Pointe-a-Pitre → Basseterre → Tortola → Santo Domingo
$649
$93 per day
Inside
December 13, 2027
Costa Serena
S M L XL
Santo Domingo → Fort-de-France → Pointe-a-Pitre → St. John's, Antigua → Basseterre → Philipsburg → Santo Domingo
$1,594
$228 per day
Suite
December 6, 2027
Costa Serena
S M L XL
Santo Domingo → Fort-de-France → Pointe-a-Pitre → Basseterre → St. John's, Antigua → Tortola → Santo Domingo
$1,609
$230 per day
Suite
January 24, 2028
Costa Serena
S M L XL
Santo Domingo → St. John's, Antigua → Fort-de-France → Pointe-a-Pitre → Basseterre → Tortola → Santo Domingo
$1,669
$238 per day
Suite
January 10, 2028
Costa Serena
S M L XL
Santo Domingo → St. John's, Antigua → Fort-de-France → Pointe-a-Pitre → Basseterre → Tortola → Santo Domingo
$1,669
$238 per day
Suite
February 28, 2028
Costa Serena
S M L XL
Santo Domingo → St. John's, Antigua → Fort-de-France → Pointe-a-Pitre → Basseterre → Tortola → Santo Domingo
$1,669
$238 per day
Suite
January 31, 2028
Costa Serena
S M L XL
Santo Domingo → St. John's, Antigua → Fort-de-France → Pointe-a-Pitre → Basseterre → Tortola → Santo Domingo
$1,669
$238 per day
Suite
January 17, 2028
Costa Serena
S M L XL
Santo Domingo → St. John's, Antigua → Fort-de-France → Pointe-a-Pitre → Basseterre → Tortola → Santo Domingo
$1,669
$238 per day
Suite

Frequently Asked Questions about Cruises from Santo Domingo

❓ How many cruises depart from Santo Domingo?

32 cruises depart from Santo Domingo, sailing in 2026-2028.

❓ How much does a cruise from Santo Domingo cost?

Fares start at $499 per person; the total depends on the cruise line, cabin, and season.

❓ What cruise lines leave from Santo Domingo?

Cruise lines sailing out of Santo Domingo include Costa.

❓ How long are cruises from Santo Domingo?

Cruises out of Santo Domingo range from 7 to 20 nights, with 7-night sailings the most common.

❓ Where do cruises from Santo Domingo go?

Popular destinations from Santo Domingo include Pointe-a-Pitre, Fort-de-France, Basseterre, St. John's, Antigua, Tortola, and Philipsburg.

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