577 South American cruises under $500/Night
March 14, 2028
7 Night South America Cruise
CruiseScore™ (3.93/5)
MSC Virtuosa
S
M
L
XL
Salvador
→
Maceió
→
Sao Paulo
→
Búzios
→
Salvador
Inside
March 8, 2028
7 Night South America Cruise
CruiseScore™ (4.09/5)
MSC Virtuosa
S
M
L
XL
Maceió
→
Sao Paulo
→
Búzios
→
Salvador
→
Maceió
Inside
March 7, 2028
7 Night South America Cruise
CruiseScore™ (4.09/5)
MSC Virtuosa
S
M
L
XL
Salvador
→
Maceió
→
Sao Paulo
→
Búzios
→
Salvador
Inside
March 1, 2028
7 Night South America Cruise
CruiseScore™ (3.98/5)
MSC Virtuosa
S
M
L
XL
Maceió
→
Sao Paulo
→
Búzios
→
Salvador
→
Maceió
Inside
February 29, 2028
7 Night South America Cruise
CruiseScore™ (3.98/5)
MSC Virtuosa
S
M
L
XL
Salvador
→
Maceió
→
Sao Paulo
→
Búzios
→
Salvador
Inside
February 23, 2028
7 Night South America Cruise
CruiseScore™ (4.09/5)
MSC Virtuosa
S
M
L
XL
Maceió
→
Sao Paulo
→
Búzios
→
Salvador
→
Maceió
Inside
February 22, 2028
7 Night South America Cruise
CruiseScore™ (4.09/5)
MSC Virtuosa
S
M
L
XL
Salvador
→
Maceió
→
Sao Paulo
→
Búzios
→
Salvador
Inside
February 16, 2028
7 Night South America Cruise
CruiseScore™ (4.09/5)
MSC Virtuosa
S
M
L
XL
Maceió
→
Sao Paulo
→
Búzios
→
Salvador
→
Maceió
Inside
February 15, 2028
7 Night South America Cruise
CruiseScore™ (4.09/5)
MSC Virtuosa
S
M
L
XL
Salvador
→
Maceió
→
Sao Paulo
→
Búzios
→
Salvador
Inside
February 9, 2028
7 Night South America Cruise
CruiseScore™ (4.09/5)
MSC Virtuosa
S
M
L
XL
Maceió
→
Sao Paulo
→
Búzios
→
Salvador
→
Maceió
Inside
LOWEST PRICE EVER
March 9, 2027
5 Night South America Cruise
CruiseScore™ (4.03/5)
MSC Musica
S
M
L
XL
Rio de Janeiro
→
Búzios
→
Ilha Grande
→
Paranagua
→
Itajai
Outside
December 8, 2026
14 Night Round World from San Antonio (Santiago), Chile Cruise
CruiseScore™ (3.91/5)
Costa Serena
S
M
L
XL
San Antonio
→
Puerto Montt
→
Puerto Chacabuco
→
Punta Arenas
→
Ushuaia
→
Puerto Madryn
→
Buenos Aires
Suite
November 2, 2027
15 Night South America Pathways: Chilean Fjords & Glaciers
CruiseScore™ (4.61/5)
Holland America Nieuw Amsterdam
S
M
L
XL
San Antonio
→
Puerto Montt
→
Puerto Chacabuco
→
Punta Arenas
→
Ushuaia
→
Port Stanley
→
Montevideo
→
Buenos Aires
→
Buenos Aires
Suite
February 29, 2028
7 Night South America Cruise
CruiseScore™ (3.89/5)
MSC Musica
S
M
L
XL
Rio de Janeiro
→
Búzios
→
Ilha Grande
→
Paranagua
→
Itajai
→
Ilhabela
→
Rio de Janeiro
Inside
December 21, 2026
5 Night South America Cruise
CruiseScore™ (3.84/5)
MSC Divina
S
M
L
XL
Sao Paulo
→
Ilha Grande
→
Búzios
→
Ilhabela
→
Sao Paulo
Suite