11 Night from San Diego to Panama City on the Crystal Serenity
Get ready for eleven nights of refreshing cruising across the sea when you reserve your outside cabin on the Crystal Serenity from San Diego to Panama City.
Spending time at extremely rare cities like San Juan del Sur, Zihuatanejo, and Acajutla makes this cruise noteworthy. This route is an uncommon one for the Serenity, As it sails it only once.
This price includes all meals, entertainment, taxes, and fees. No surprises at checkout! Especially exciting is that if you act now you can get a window outside stateroom for the price of an interior outside stateroom!
The Crystal Serenity
Over 700 travelers can sail on the top-rated flagship of the Serenity class, based in and refurbished only this year ago in 2026.
The Serenity Crystal offers a gym, a spa, a jacuzzi, a ping pong table, and a casino.
- Ship class
- Serenity
- Built
- 2003
- Refurbished
- 2026
- Guests
- 740
- Crew
- 655
- Length
- 820 ft
Your Itinerary
This sailing includes four days at sea and six days in port. High points include a long stop in Manzanillo as well as visits to exotic destinations like San Juan del Sur, Zihuatanejo, and Acajutla.
© OpenStreetMap · © ESA WorldCover
Book Your Cruise
Since it was first listed on July 17th of this year, The price of an outside room on this itinerary has varied between $5,000 and $5,300 including taxes and port charges. At only $300 more than the all time low of $5,000 now is a great time to secure your outside stateroom
Photos show a typical cabin in each class. Layout and decor vary by category.
Resources
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OutlookPrintable CruiseSheet
One page with the route, the day-by-day schedule, typical weather and a notes box for each day.
Alternate Sailings
The Serenity sails this route once next year, but doesn't sail it this year. This is the only ship that sails this exact route.
No other departures of this route are on sale right now.
Show alternate dates for this cruise → Show all cruises that sail this route →
Data as of Oct 11, 2026