11 Night from San Diego to Panama City on the Crystal Serenity
Get ready for eleven nights of refreshing cruising around the Caribbean when you reserve your outside cabin on the Crystal Serenity from San Diego to Panama City.
Spending time at extremely rare cities like San Juan del Sur, Zihuatanejo, and Acajutla makes this cruise noteworthy. This route is an uncommon one for the Serenity, As it sails it only once.
This price includes all meals, entertainment, taxes, and fees. No surprises at checkout! Especially exciting is that if you act now you can get a window outside stateroom for the price of an interior outside stateroom!
The Crystal Serenity
Based in Europe and refurbished less than this year ago in 2026, over 700 travelers can travel on the Serenity Crystal, the top-rated namesake of Crystal's class.
The Serenity Crystal is home to a gym, a casino, a jacuzzi, a spa, and a ping pong table.
Your Itinerary
This sailing includes six days in port and four days at sea. High points include a long stop in Manzanillo as well as visits to rare cities like San Juan del Sur, Zihuatanejo, and Acajutla.
Alternate Sailings
The Serenity sails this route once next year, but doesn't sail it this year. No other ship sails this exact same route. In the accompanying graphic you can see a visualization of when this ship sails as well as the relative price for an outside cabin.
Book Your Cruise
Since it was first listed on July 17th of this year, The price of an outside room on this itinerary has varied between $5,000 and $5,300 including taxes and port charges. The accompanying graph displays the cost over time for the various classes of cabin. At only $300 more expensive than the all time low of $5,000 now is a great time to reserve your outside stateroom
Last Updated: Aug 30, 2026
Last Modified: Aug 8, 2026