11 Night from San Diego to Panama City on the Crystal Serenity
Prepare yourself for eleven nights of tropical travel through the Caribbean when you set sail with the Crystal Serenity from San Diego to Panama City.
Stopping at extremely rare stops like Zihuatanejo, San Juan del Sur, and Acajutla makes this sailing particularly exciting. This route is an interesting one for the Serenity. In fact, it sails it just once.
We include all all entertainment, meals, taxes, and port fees in this, so that you can compare sailings easily. Book quickly, because the price of this itinerary is moving upwards! Reserve your outside stateroom before the price rises.
The Crystal Serenity
Based in Europe and refurbished only this year ago in 2026, more than 700 passengers can cruise on the Serenity Crystal, the highly-rated namesake of Crystal's class.
The Serenity Crystal is home to a spa, a ping pong table, a gym, a jacuzzi, and a casino.
Your Itinerary
This sailing consists of four days at sea and six port days. Highlights include visits to rare stops like Zihuatanejo, San Juan del Sur, and Acajutla as well as a long stop in Manzanillo.
Alternate Sailings
The Serenity sails this route once next year, but doesn't sail it this year. This is the only ship that sails this exact route. In the accompanying graphic you can see a visualization of when this ship sails as well as the relative price for an outside cabin.
Book Your Cruise
The accompanying graph indicates the cost over time for the various classes of cabin. Since it was first listed on July 17th of this year, The cost of this sailing has fluctuated between $5,000 and $5,300 for an outside stateroom, inclusive of taxes and port fees. This itinerary has just risen in price, so secure your outside stateroom now before it goes up again.
Last Updated: Aug 10, 2026
Last Modified: Aug 8, 2026