21 Night Panama Canal & Eastern Caribbean: U.S. Virgin Islands Cruise aboard the Holland America Nieuw Amsterdam

Get ready for twenty-one nights of refreshing travel across the sea when you book your cabin on the Holland America Nieuw Amsterdam from Ft. Lauderdale and back again.

Spending time at very uncommon ports such as Puerto Limon, Colon, and Half Moon Cay makes this cruise particularly interesting. This route is an uncommon one for the Nieuw Amsterdam. As a matter of fact, it sails it just once.

At less than $130 a day, this represents a solid bargain. Our price is the total price, including all taxes and fees.

Jacuzzi
Day 8: Colon

The Holland America Nieuw Amsterdam

Based in Alaska and refurbished just three years ago in 2023, over 2,100 passengers can travel on this top-rated Signature class cruise ship.

The Nieuw Amsterdam Holland America wows guests with a gym, a spa, a casino, and seven jacuzzis.

Holland America Nieuw Amsterdam
Day 18: Tortola

Your Itinerary

This itinerary includes eight days at sea and twelve days in port. Major features include visits to extremely rare stops like Puerto Limon, Colon, and Half Moon Cay in addition to a long stop in St. Thomas.

DatePortArriveDepart
Sun, Jan 17Fort Lauderdale, FL 4:00pm
Mon, Jan 18Half Moon Cay, Bahamas 8:00am5:00pm
Tue, Jan 19At Sea
Wed, Jan 20At Sea
Thu, Jan 21Oranjestad, Aruba 8:00am5:00pm
Fri, Jan 22At Sea
Sat, Jan 23Cartagena, Colombia 7:00am2:00pm
Sun, Jan 24Panama Canal (Cruising) 2:00pm3:00pm
Gatun Lake, Panama (Cruising)
Colon, Panama 5:00pm9:00pm
Mon, Jan 25Puerto Limon, Costa Rica 7:30am4:30pm
Tue, Jan 26At Sea
Wed, Jan 27Georgetown, Cayman Islands 7:00am4:00pm
Thu, Jan 28At Sea
Fri, Jan 29Fort Lauderdale, FL 7:00am4:00pm
Sat, Jan 30At Sea
Sun, Jan 31At Sea
Mon, Feb 1St. John's, Antigua 9:00am6:00pm
Tue, Feb 2St. Thomas, USVI 8:00am11:00pm
Wed, Feb 3Tortola, BVI 8:00am6:00pm
Thu, Feb 4San Juan, Puerto Rico 8:00am5:00pm
Fri, Feb 5At Sea
Sat, Feb 6Half Moon Cay, Bahamas 8:00am3:00pm
Sun, Feb 7Fort Lauderdale, FL 7:00am
January 17th, 2027  - Panama Canal & Eastern Caribbean: U.S. Virgin Islands Cruise on the Holland America Nieuw Amsterdam
Your Route
Day 16: St. John's
Day 17: St. Thomas
Day 7: Cartagena
Spa
Day 5: Aruba
Gym

Alternate Sailings

The Nieuw Amsterdam sails this route once next year, but doesn't sail it this year. This is the only ship that sails this exact route. In the accompanying graphic you can see a visualization of when this ship sails as well as the relative price.

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec
2026
2027
$2,639 $2,639
Sold Out

Book Your Cruise

Since being listed fifteen months ago, The cost of this cruise has ranged between $2,289 and $3,524 for a stateroom, inclusive of $0 in taxes and port charges. The accompanying graph shows the price over time for each class of cabin. Right now this itinerary is just fifteen percent more expensive than the all time low of $2,289 so reserve your room now before it goes up.

inside
outside
balcony
suite
$2,639
$3,039
$4,349
$7,809
$125.67/day
$144.71/day
$207.10/day
$371.86/day
Book Book Book Book

Get Weekly Cruise Deals

Want to hear about the best deals and cruise tips every week? Sign up for our free weekly VIP Newsletter, customized exactly to your preferences!

Last Updated: Jun 25, 2026

Last Modified: Jun 25, 2026

Continue Booking from $2,639 Continue Booking