21 Night Panama Canal Cruise aboard the Holland America Nieuw Amsterdam

Set sail with the Holland America Nieuw Amsterdam and settle in for twenty-one nights of breathtaking travel across the sea from Vancouver to Ft. Lauderdale!

Spending time at rare ports such as Puerto Chiapas, Huatulco, and Acajutla makes this cruise special. This route is an uncommon one for the Nieuw Amsterdam, As it sails it only once.

Act now, because the price of this sailing is on the way up! Reserve your cabin before the price moves upwards. This includes all entertainment, meals, port fees, and taxes. No surprises! Offered at less than $130 per day, this deal is solid.

Gym
Day 18: Cartagena

The Holland America Nieuw Amsterdam

Over 2,100 travelers can sail on this highly-rated Signature class ship, based in Alaska and refurbished just three years ago in 2023.

The Nieuw Amsterdam Holland America wows guests with seven jacuzzis, a casino, a gym, and a spa.

Holland America Nieuw Amsterdam
Day 22: Ft. Lauderdale

Your Itinerary

This sailing includes nine port days and eleven days at sea. High points include visits to rare destinations like Puerto Chiapas, Huatulco, and Acajutla plus long stops in San Francisco and Puerto Quetzal.

DatePortArriveDepart
Sun, Sep 27Vancouver, Canada 4:00pm
Mon, Sep 28At Sea
Tue, Sep 29At Sea
Wed, Sep 30San Francisco, CA 7:00am9:00pm
Thu, Oct 1At Sea
Fri, Oct 2San Diego, CA 7:00am4:00pm
Sat, Oct 3At Sea
Sun, Oct 4At Sea
Mon, Oct 5Puerto Vallarta, Mexico 8:00am5:00pm
Tue, Oct 6At Sea
Wed, Oct 7Huatulco, Mexico 10:00am5:00pm
Thu, Oct 8Puerto Chiapas, Mexico 8:00am5:00pm
Fri, Oct 9Puerto Quetzal, Guatemala 6:00am8:00pm
Sat, Oct 10Acajutla, El Salvador 7:00am5:00pm
Sun, Oct 11At Sea
Mon, Oct 12At Sea
Tue, Oct 13Panama Canal (Cruising) 7:00pm7:00pm
Wed, Oct 14Cartagena, Colombia 12:00pm6:00pm
Thu, Oct 15At Sea
Fri, Oct 16At Sea
Sat, Oct 17Half Moon Cay, Bahamas 8:00am2:00pm
Sun, Oct 18Fort Lauderdale, FL 7:00am
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Print your CruiseSheet (PDF) one page with the route, schedule, weather & a notes box for each day
September 27th, 2026  - Panama Canal Cruise on the Holland America Nieuw Amsterdam
Your Route
Spa
Jacuzzi
Day 4: San Francisco
Day 6: San Diego
Day 11: Huatulco
Day 9: Puerto Vallarta

Alternate Sailings

The Nieuw Amsterdam sails this route once this year. No other ship sails this exact same route. In the accompanying graphic you can see a visualization of when this ship sails as well as the relative price.
Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec
2026
2027
2028
$2,694 $2,694
Sold Out

Book Your Cruise

Since it was first listed on April 7th of last year, The price of a room on this itinerary has varied between $2,514 and $3,360 including $0 in taxes and port fees. The accompanying graph displays the cost over time for the various types of cabin. At only $180 more expensive than the all time low of $2,514 now is a great time to lock in your stateroom

inside
outside
balcony
suite
$2,694
$2,944
$3,644
$6,444
$128.29/day
$140.19/day
$173.52/day
$306.86/day
Book Book Book Book

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Last Updated: Jul 14, 2026

Last Modified: Jul 10, 2026

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