Rome is served by the port of Civitavecchia, but isn't actually a cruise port. In total, the cruise port of Civitavecchia is the eighth most popular cruise terminal in the world, departure point of over two hundred and eighty annual sailings from Costa, MSC, Norwegian and more to the Mediterranean and Europe.
Cruises departing from Rome during the the peak season of summer are considerably more expensive than the the low season of winter. On average sailings from Rome are moderately expensive compared to other ports. The graph below shows the monthly average cost per day for cruises from Rome.