Rome is served by the port of Civitavecchia, but is not a cruise port. Combined, the port of Civitavecchia is the fifth most departed-from cruise port, as the embarkation point of around three hundred and sixty annual sailings from Norwegian, Cunard, Royal Caribbean and more to Europe and the Mediterranean.
Overall cruises from Rome are somewhat inexpensive compared to other ports. Cruises leaving from Rome during the the peak season of summer are much more expensive than the the low season of winter. The diagram below shows the monthly average cost per day for cruises from Rome.