Crystal Serenity 11-Night Panama City to San Diego
Crystal Serenity (Crystal) sails this 11-night route from Panama City to San Diego on 1 upcoming date (Dec 2026), from $5,400 per person. Every departure below links to its own page with live cabin prices, the full itinerary and online booking.
Ports on this route
Fuerte Amador → Puntarenas → Playa Flamingo → Acajutla → Zihuatanejo → Manzanillo → Puerto Vallarta → San Diego
All upcoming departures
NEW TODAY
December 10, 2026
11 Night Caribbean Cruise from Panama City to San Diego
CruiseScore™ (5.00/5)
Crystal Serenity
S
M
L
XL
Panama City
→
Puntarenas
→
Playa Flamingo
→
Acajutla
→
Zihuatanejo
→
Manzanillo
→
Puerto Vallarta
→
San Diego
Outside
Outside
