Crystal Serenity 28-Night Fort Lauderdale to San Diego
Crystal Serenity (Crystal) sails this 28-night route from Fort Lauderdale to San Diego on 1 upcoming date (Nov 2026), from $15,000 per person. Every departure below links to its own page with live cabin prices, the full itinerary and online booking.
Ports on this route
Port Everglades → Nassau → Samana → San Juan → Jost Van Dyke → Oranjestad → Cartagena, Colombia → Willemstad → Kralendijk → Oranjestad → Santa Marta → Panama Canal → Fuerte Amador → Puntarenas → Playa Flamingo → Acajutla → Zihuatanejo → Manzanillo → Puerto Vallarta → San Diego
All upcoming departures
NEW TODAY
November 23, 2026
28 Night Westbound Panama Canal Cruise from Fort Lauderdale to San Diego
CruiseScore™ (4.96/5)
Crystal Serenity
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M
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XL
Fort Lauderdale
→
Nassau
→
Samana
→
San Juan
→
Jost Van Dyke
→
Oranjestad
→
Cartagena, Colombia
→
Willemstad
→
Kralendijk
→
Oranjestad
→
Santa Marta
→
Panama City
→
Puntarenas
→
Playa Flamingo
→
Acajutla
→
Zihuatanejo
→
Manzanillo
→
Puerto Vallarta
→
San Diego
Inside
Inside
