Holland America Oosterdam 21-Night Athens to Barcelona
Holland America Oosterdam (Holland America) sails this 21-night route from Athens to Barcelona on 2 upcoming dates (Oct 2026 through May 2027), from $3,999 per person. Every departure below links to its own page with live cabin prices, the full itinerary and online booking.
Ports on this route
Piraeus → Mykonos → Istanbul → Kuşadası → Kos → Rhodes → Piraeus → Katakolon → Saranda → Valletta → Messina → Messina Strait → Naples → Civitavecchia → Strait of Bonifacio → Ajaccio → Villefranche-sur-Mer → Barcelona
All upcoming departures
PRICE RISING
October 14, 2026
21 Night Adriatic Splendor Collectors' Voyage
CruiseScore™ (4.56/5)
Holland America Oosterdam
S
M
L
XL
Athens
→
Mykonos
→
Istanbul
→
Ephesus
→
Kos
→
Rhodes
→
Athens
→
Olympia
→
Saranda
→
Valletta
→
Messina
→
Naples
→
Rome
→
Ajaccio
→
Villefranche-sur-Mer
→
Barcelona
Suite
May 4, 2027
21 Night Greek Isles with Istanbul, Dubrovnik, Italy & Spain Cruise
CruiseScore™ (4.45/5)
Holland America Oosterdam
S
M
L
XL
Athens
→
Ephesus
→
Istanbul
→
Mykonos
→
Chania
→
Olympia
→
Saranda
→
Dubrovnik
→
Trieste
→
Zadar
→
Dubrovnik
→
Corfu
→
Messina
→
Naples
→
Rome
→
Barcelona
Inside
