MSC Opera 4-Night Rome to Barcelona
MSC Opera (MSC) sails this 4-night route from Rome to Barcelona on 1 upcoming date (Oct 2026), from $490 per person. Every departure below links to its own page with live cabin prices, the full itinerary and online booking. Prices refresh daily.
Ports on this route
Civitavecchia → Portofino → Livorno → Marseille → Barcelona
All upcoming departures
October 29, 2026
4 Night Grand Voyages
CruiseScore™ (3.48/5)
MSC Opera
S
M
L
XL
Rome
→
Portofino
→
Florence
→
Marseille
→
Barcelona
Inside
Inside
