Book your cabin on the Royal Caribbean Odyssey of the Seas and prepare for seven nights of leisurely sailing through the sea from Rome and back again!
Aboard this Labor Day sailing you will stop at common destinations such as Naples plus unusual destinations such as Santorini, Mykonos, and Kuşadası. This is a frequent route for the Odyssey of the Seas.
We include all entertainment, meals, port fees, and taxes in this, so that you can compare trips easily.
Based in Rome and Bayonne and refurbished just this year ago in 2026, more than 3,800 guests can cruise comfortably on this top-rated Quantum Ultra class ship.
Want to experience weightlessness in an indoor skydiving chamber, drink to the future at a bar with a robotic bartender, or surf on the Flowrider artificial surf wave? These activities are exclusive to Royal Caribbean and are all found on the Odyssey of the Seas Royal Caribbean. Want more? Experience rare features like a bumper car track, a trampoline park, and a roller skating rink.
The Odyssey of the Seas Royal Caribbean also offers a casino, a waterslide, a solarium, a gym, a basketball court, an outdoor movie theater, a spa, and a jacuzzi.
This cruise spends two days at sea and four port days. High points include visits to more exotic ports like Santorini, Mykonos, and Kuşadası.
| Date | Port | Arrive | Depart |
|---|---|---|---|
| Sun, Sep 5 | Civitavecchia, Italy (Rome) | ||
| Mon, Sep 6 | At Sea | ||
| Tue, Sep 7 | Santorini, Greece | 9:00am | 5:00pm |
| Wed, Sep 8 | Kuşadası, Turkey (Ephesus) | 9:00am | 5:00pm |
| Thu, Sep 9 | Mykonos, Greece | 9:00am | 5:00pm |
| Fri, Sep 10 | At Sea | ||
| Sat, Sep 11 | Naples, Italy | 9:00am | 5:00pm |
| Sun, Sep 12 | Civitavecchia, Italy (Rome) | 9:00am |
The Odyssey of the Seas sails this route once this year in addition to twenty-five times next year. This is the only ship that sails this exact route. In the accompanying graphic you can see a visualization of when this ship sails as well as the relative price.
The accompanying graph indicates the cost over time for all types of cabin. Since being listed eight months ago, The cost of this sailing has ranged between $1,253 and $1,532 for a stateroom, inclusive of $0 in taxes and port fees. Right now this cruise is just $166 more than the all time low of $1,253 so secure your stateroom now before it goes up.
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Last Updated: Jun 24, 2026
Last Modified: Jun 24, 2026