15 Night Panama Canal Cruise aboard the Royal Caribbean Serenade of the Seas

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Join the Royal Caribbean Serenade of the Seas and settle in for fifteen nights of luxurious sailing across the sea from Tampa to Los Angeles!

Spending time in very uncommon stops such as Puerto Quetzal, Puntarenas, and Puerto Vallarta makes this trip special. This route is an interesting one for the Serenade of the Seas, As it sails it only once.

Offered at less than $110 per day, this deal is very strong. The price is the total you pay, no surprises.


The Royal Caribbean Serenade of the Seas

Based in San Diego and Vancouver and refurbished only one year ago in 2025, over 2,100 travelers can travel comfortably on this top-rated Radiance class ship.

The Serenade of the Seas Royal Caribbean boasts a ping pong table, a gym, three jacuzzis, a solarium, a casino, a basketball court, a spa, and an outdoor movie theater.

Ship class
Radiance
Built
2003
Refurbished
2025
Guests
2,148
Crew
859
Length
961 ft
Royal Caribbean Serenade of the Seas
Ping Pong Table

Your Itinerary

This cruise spends nine days at sea and five days in port. High points include a long stop in Panama Canal in addition to visits to rare cities like Puerto Quetzal, Puntarenas, and Puerto Vallarta.

Map of this cruise's route
© OpenStreetMap · © ESA WorldCover
Sat22April 22ndSaturday
4:00pm
4:00pm
Sun23April 23rdSunday
At Sea
Mon24April 24thMonday
8:00am – 5:00pm
Tue25April 25thTuesday
At Sea
Wed26April 26thWednesday
7:00am – 3:00pm
Thu27April 27thThursday
Panama Canal (Cruising)
Fri28April 28thFriday
At Sea
Sat29April 29thSaturday
8:00am – 6:00pm
Sun30April 30thSunday
At Sea
Mon1May 1stMonday
8:00am – 6:00pm
Tue2May 2ndTuesday
At Sea
Wed3May 3rdWednesday
At Sea
Thu4May 4thThursday
8:00am – 6:00pm
Fri5May 5thFriday
At Sea
Sat6May 6thSaturday
At Sea
Sun7May 7thSunday
6:00am
6:00am
Day 3Georgetown
Day 5Cartagena, Colombia
Day 13Puerto Vallarta
Day 16Los Angeles

Book Your Cruise

Since it was first listed on October 3rd of this year, The cost of a room on this sailing has varied between $1,423 and $1,699 inclusive of taxes and port fees. Now this cruise is just $164 more expensive than the all time low of $1,423 so secure your cabin now before it goes up.

Photos show a typical cabin in each class. Layout and decor vary by category.


Resources

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Printable CruiseSheet

One page with the route, the day-by-day schedule, typical weather and a notes box for each day.


Alternate Sailings

This is the only ship that sails this exact route.

No other departures of this route are on sale right now.

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Data as of Oct 18, 2026

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Guests in this cabin
Ages at the time of sailing

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