577 South American cruises under $500/Night
December 14, 2027
7 Night South America Cruise
CruiseScore™ (3.97/5)
MSC Virtuosa
S
M
L
XL
Salvador
→
Maceió
→
Sao Paulo
→
Búzios
→
Salvador
Inside
December 8, 2027
7 Night South America Cruise
CruiseScore™ (3.95/5)
MSC Virtuosa
S
M
L
XL
Maceió
→
Sao Paulo
→
Búzios
→
Salvador
→
Maceió
Inside
December 7, 2027
7 Night South America Cruise
CruiseScore™ (3.95/5)
MSC Virtuosa
S
M
L
XL
Salvador
→
Maceió
→
Sao Paulo
→
Búzios
→
Salvador
Inside
October 12, 2027
21 Night South American Cruise from San Diego to San Antonio
CruiseScore™ (4.82/5)
Holland America Nieuw Amsterdam
S
M
L
XL
San Diego
→
Cabo San Lucas
→
Huatulco
→
Puerto Quetzal
→
Puntarenas
→
Manta
→
Salaverry
→
Lima
→
Pisco
→
Arica
→
Coquimbo
→
San Antonio
Outside
March 10, 2027
7 Night Round Trip South American Cruise from Buenos Aires
CruiseScore™ (4.02/5)
Costa Diadema
S
M
L
XL
Buenos Aires
→
Montevideo
→
Itajai
→
Sao Paulo
→
Buenos Aires
Suite
December 16, 2026
7 Night South America Cruise
CruiseScore™ (3.95/5)
MSC Virtuosa
S
M
L
XL
Maceió
→
Sao Paulo
→
Búzios
→
Salvador
→
Maceió
Balcony
March 18, 2028
7 Night South America Cruise
CruiseScore™ (3.93/5)
MSC Virtuosa
S
M
L
XL
Sao Paulo
→
Búzios
→
Salvador
→
Maceió
→
Sao Paulo
Inside
March 11, 2028
7 Night South America Cruise
CruiseScore™ (4.09/5)
MSC Virtuosa
S
M
L
XL
Sao Paulo
→
Búzios
→
Salvador
→
Maceió
→
Sao Paulo
Inside
March 4, 2028
7 Night South America Cruise
CruiseScore™ (3.98/5)
MSC Virtuosa
S
M
L
XL
Sao Paulo
→
Búzios
→
Salvador
→
Maceió
→
Sao Paulo
Inside
February 26, 2028
7 Night South America Cruise
CruiseScore™ (4.09/5)
MSC Virtuosa
S
M
L
XL
Sao Paulo
→
Búzios
→
Salvador
→
Maceió
→
Sao Paulo
Inside
February 19, 2028
7 Night South America Cruise
CruiseScore™ (4.09/5)
MSC Virtuosa
S
M
L
XL
Sao Paulo
→
Búzios
→
Salvador
→
Maceió
→
Sao Paulo
Inside
February 12, 2028
7 Night South America Cruise
CruiseScore™ (4.09/5)
MSC Virtuosa
S
M
L
XL
Sao Paulo
→
Búzios
→
Salvador
→
Maceió
→
Sao Paulo
Inside
January 2, 2029
12 Night Round Trip Patagonia Cruise from Buenos Aires
CruiseScore™ (4.61/5)
Celebrity Equinox
S
M
L
XL
Buenos Aires
→
Montevideo
→
Ushuaia
→
Punta Arenas
→
Puerto Madryn
→
Punta del Este
→
Buenos Aires
Inside
LOWEST PRICE EVER
December 22, 2026
9 Night South America Cruise
CruiseScore™ (3.80/5)
MSC Splendida
S
M
L
XL
Rio de Janeiro
→
Ilhabela
→
Camboriu
→
Punta del Este
→
Buenos Aires
→
Ilhabela
→
Rio de Janeiro
Inside
December 13, 2026
4 Night South America Cruise
CruiseScore™ (3.83/5)
MSC Musica
S
M
L
XL
Sao Paulo
→
Búzios
→
Ilha Grande
→
Sao Paulo
Suite