21 Night from San Diego to San Antonio on the Holland America Nieuw Amsterdam
Get ready for twenty-one nights of exciting sailing through the sea when you join the Holland America Nieuw Amsterdam from San Diego to San Antonio.
This cruise is notable because you will exclusively call on extremely rare cities such as Coquimbo, Arica, and Salaverry. This route is a special one for the Nieuw Amsterdam. As a matter of fact, this is the only time it's scheduled to sail it!
We include all entertainment, meals, port fees, and taxes in the price, so there are no surprises. At under $105 per day, this represents a very strong value.
The Holland America Nieuw Amsterdam
Based in Fort Lauderdale and refurbished only three years ago in 2023, more than 2,100 cruisers can cruise comfortably on this highly-rated Signature class vessel.
The Nieuw Amsterdam Holland America is home to seven jacuzzis, a spa, a casino, and a gym.
Your Itinerary
This cruise is made up of twelve port days and eight days at sea. High points include a long stop in Pisco plus visits to rare stops like Coquimbo, Arica, and Salaverry.
Alternate Sailings
The Nieuw Amsterdam sails this route once next year, but doesn't sail it this year. No other ship sails this exact same route. In the accompanying graphic you can see a visualization of when this ship sails as well as the relative price.
Book Your Cruise
Since being listed seven months ago, The price of this itinerary has varied between $2,139 and $2,909 for a cabin, including taxes and port fees. The accompanying graph displays the price over time for the different types of cabin. Today this cruise is at its minimum price, so secure your stateroom now before it increases.
Last Updated: Sep 14, 2026
Last Modified: Sep 8, 2026