8 Night from Cartagena, Colombia to Panama City on the Crystal Serenity
Step aboard the Crystal Serenity and settle in for eight nights of exciting cruising across the sea from Cartagena, Colombia to Panama City!
This sailing is special because you'll only stop in extremely rare stops such as Santa Marta, Kralendijk, and Fuerte Amador. This route is an unusual one for the Serenity, As it sails it just once.
We include all meals, entertainment, taxes, and fees in this, so there are no sneaky extra fees. Especially exciting is that if you act now you can reserve an oceanview outside room for the interior price!
The Crystal Serenity
Based in and refurbished only this year ago in 2026, more than 700 guests can sail comfortably on the Serenity Crystal, the top-rated flagship of Crystal's Serenity class.
The Serenity Crystal has a spa, a casino, a ping pong table, a jacuzzi, and a gym.
- Ship class
- Serenity
- Built
- 2003
- Refurbished
- 2026
- Guests
- 740
- Crew
- 655
- Length
- 820 ft
Your Itinerary
This itinerary spends two sea days and five days in port. Major features include long stops in Panama Canal, Kralendijk, and Willemstad as well as visits to exotic destinations like Santa Marta and Fuerte Amador.
© OpenStreetMap · © ESA WorldCover
Book Your Cruise
Since being listed two months ago, the price of this cruise has remained right at $4,200 for an outside cabin. Now this itinerary is at its minimum price, so lock in your outside room now before it increases.
Photos show a typical cabin in each class. Layout and decor vary by category.
Resources
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One page with the route, the day-by-day schedule, typical weather and a notes box for each day.
Alternate Sailings
The Serenity sails this route once this year. No other ship sails this exact same route.
No other departures of this route are on sale right now.
Show alternate dates for this cruise → Show all cruises that sail this route →
Data as of Oct 13, 2026