8 Night from Cartagena, Colombia to Panama City on the Crystal Serenity
Step aboard the Crystal Serenity and settle in for eight nights of exciting cruising across the sea from Cartagena, Colombia to Panama City!
This sailing is special because you'll only stop in extremely rare stops such as Santa Marta, Fuerte Amador, and Kralendijk. This route is an unusual one for the Serenity, As it sails it just once.
We include all meals, entertainment, taxes, and fees in this, so there are no sneaky extra fees. Especially exciting is that if you act now you can reserve an oceanview outside room for the interior price!
The Crystal Serenity
The Serenity Crystal is the top-rated flagship of the class, based in Europe, that can house comfortably more than 700 people.
The Serenity Crystal delights guests with a gym, a ping pong table, a spa, a jacuzzi, and a casino.
Your Itinerary
This itinerary includes two days at sea and five days in port. Highlights include long stops in Panama Canal, Kralendijk, and Willemstad as well as visits to exotic destinations like Santa Marta and Fuerte Amador.
Alternate Sailings
The Serenity sails this route once this year. This is the only ship that sails this exact route. In the accompanying graphic you can see a visualization of when this ship sails as well as the relative price for an outside cabin.
Book Your Cruise
Since being listed 21 days ago, the price of this cruise has remained right at $4,200 for an outside cabin. The accompanying graph displays the cost over time for the various types of cabin. Today this cruise is at an all time low, so reserve your outside cabin now before it rises.
Last Updated: Sep 3, 2026
Last Modified: Aug 13, 2026