8 Night from Cartagena, Colombia to Panama City on the Crystal Serenity

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Reserve your outside cabin on the Crystal Serenity and settle in for eight nights of exciting cruising across the sea from Cartagena, Colombia to Panama City!

This trip is noteworthy because you'll exclusively visit extremely rare destinations such as Santa Marta, Fuerte Amador, and Kralendijk. This route is an uncommon one for the Serenity, But this is the lowest price sailing on it.

This is the total price for an outside cabin, including all meals, entertainment, port charges, and taxes.

Day 6: Santa Marta
Day 5: Oranjestad

The Crystal Serenity

The Serenity Crystal, the namesake of Crystal's class, is a top-rated class ship based in Europe that can house more than 700 cruisers.

The Serenity Crystal delights guests with a ping pong table, a casino, a jacuzzi, a gym, and a spa.

Crystal Serenity

Your Itinerary

This itinerary includes six port days and one sea day. High points include long stops in Panama Canal, Kralendijk, and Willemstad in addition to visits to rare destinations like Santa Marta and Fuerte Amador.

Wed2December 2ndWednesday
7:00pm
Thu3December 3rdThursday
At Sea
Fri4December 4thFriday
7:00am – 8:00pm
Sat5December 5thSaturday
8:00am – 7:00pm
Sun6December 6thSunday
7:00am – 5:00pm
7:00am – 5:00pm
Mon7December 7thMonday
9:00am – 7:00pm
Tue8December 8thTuesday
At Sea
Wed9December 9thWednesday
Panama Canal (Cruising)
8:00pm – 6:00pm8:00pm – 6:00pm
Fri11December 11thFriday
At Sea
Sat12December 12thSaturday
7:00am
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Print your CruiseSheet (PDF) one page with the route, schedule, weather & a notes box for each day
December 2nd, 2026 - Cartagena, Colombia to Panama City Cruise on the Crystal Serenity
Your Route
Day 3: Willemstad
Day 4: Kralendijk

Alternate Sailings

The Serenity sails this route two times this year. This is the only ship that sails this exact route. In the accompanying graphic you can see a visualization of when this ship sails as well as the relative price for an outside cabin.

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec
2026
2027
2028
$4,200 $5,000
Sold Out

See every departure of this route →


Book Your Cruise

Since being listed 1 days ago, the price of this cruise has remained steady at $4,200 for an outside cabin. This graph shows the price over time for all types of cabin. Now this itinerary is at an all time low, so reserve your outside stateroom now before it goes up.

outside
balcony
suite
$4,200
$5,000
$4,700
$525.00/day
$587.50/day
$587.50/day
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Last Updated: Aug 14, 2026

Last Modified: Aug 13, 2026

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