Crystal Serenity 8-Night Cartagena, Colombia to Panama City

Crystal Serenity 8-Night Cartagena, Colombia to Panama City

Crystal Serenity (Crystal) sails this 8-night route from Cartagena, Colombia to Panama City on 2 upcoming dates (Dec 2026), from $4,200 per person. Every departure below links to its own page with live cabin prices, the full itinerary and online booking.

Ports on this route

Cartagena, Colombia → Willemstad → Kralendijk → Oranjestad → Santa Marta → Panama Canal → Fuerte Amador → Panama Canal → Fuerte Amador → Puntarenas

All upcoming departures

NEW TODAY
8 Night Cartagena, Colombia to Panama City cruise
December 2, 2026
Crystal Serenity
S M L XL
Cartagena, Colombia → Cartagena, Colombia → Willemstad → Kralendijk → Oranjestad → Santa Marta → Panama City → Panama City
$4,200
$525 per day
Inside
NEW TODAY
8 Night Cartagena, Colombia to Panama City cruise
December 2, 2026
Crystal Serenity
S M L XL
Cartagena, Colombia → Cartagena, Colombia → Willemstad → Kralendijk → Oranjestad → Santa Marta → Panama City → Panama City
$5,000
$625 per day
Inside

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