Crystal Serenity 8-Night Cartagena, Colombia to Panama City
Crystal Serenity (Crystal) sails this 8-night route from Cartagena, Colombia to Panama City on 1 upcoming date (Dec 2026), from $4,200 per person. Every departure below links to its own page with live cabin prices, the full itinerary and online booking.
Ports on this route
Cartagena, Colombia → Willemstad → Kralendijk → Oranjestad → Santa Marta → Panama Canal → Fuerte Amador
All upcoming departures
December 2, 2026
8 Night Westbound Panama Canal Cruise from Cartagena, Colombia to Panama City
CruiseScore™ (4.94/5)
Crystal Serenity
S
M
L
XL
Cartagena, Colombia
→
Willemstad
→
Kralendijk
→
Oranjestad
→
Santa Marta
→
Panama City
→
Panama City
Outside
Outside
