21 Night Panama Canal & Eastern Caribbean: U.S. Virgin Islands Cruise aboard the Holland America Nieuw Amsterdam

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Prepare for twenty-one nights of luxurious cruising around the Caribbean when you set sail with the Holland America Nieuw Amsterdam from Fort Lauderdale and back again.

Aboard this trip you'll spend time at usual stops like Port Everglades and San Juan as well as very uncommon stops like Puerto Limon and Colon. This route is an interesting one for the Nieuw Amsterdam, But this is the least expensive sailing.

We include all entertainment, meals, port fees, and taxes in the price, so that you can compare cruises easily. With a cost of less than $130 a day, this deal is good.

Day 5: Oranjestad
Day 8: Colon

The Holland America Nieuw Amsterdam

The Nieuw Amsterdam Holland America, based in Fort Lauderdale and refurbished less than three years ago in 2023, is a top-rated Signature class ship that can accomodate comfortably more than 2,100 passengers.

The Nieuw Amsterdam Holland America offers guests a spa, a casino, a gym, and seven jacuzzis.

Holland America Nieuw Amsterdam
Day 17: St. Thomas

Your Itinerary

This itinerary is made up of twelve port days and eight days at sea. High points include visits to extremely rare cities like Puerto Limon and Colon in addition to a long stop in St. Thomas.

Sun28February 28thSunday
4:00pm
Mon1March 1stMonday
8:00am – 5:00pm
Tue2March 2ndTuesday
At Sea
Wed3March 3rdWednesday
At Sea
Thu4March 4thThursday
8:00am – 5:00pm
8:00am – 5:00pm
Fri5March 5thFriday
At Sea
Sat6March 6thSaturday
7:00am – 2:00pm
Sun7March 7thSunday
Gatun Lake, Panama (Cruising)
Panama Canal (Cruising)
5:00pm – 9:00pm
5:00pm – 9:00pm
Mon8March 8thMonday
7:30am – 4:30pm
Tue9March 9thTuesday
At Sea
Wed10March 10thWednesday
7:00am – 4:00pm
Thu11March 11thThursday
At Sea
Fri12March 12thFriday
7:00am – 4:00pm
Sat13March 13thSaturday
At Sea
Sun14March 14thSunday
At Sea
Mon15March 15thMonday
9:00am – 6:00pm
Tue16March 16thTuesday
8:00am – 11:00pm
8:00am – 11:00pm
Wed17March 17thWednesday
8:00am – 6:00pm
8:00am – 6:00pm
Thu18March 18thThursday
8:00am – 5:00pm
Fri19March 19thFriday
At Sea
Sat20March 20thSaturday
8:00am – 3:00pm
Sun21March 21stSunday
7:00am
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Print my CruiseSheet (PDF) one page with the route, schedule, weather & a notes box for each day
February 28th, 2027  - Panama Canal & Eastern Caribbean: U.S. Virgin Islands Cruise on the Holland America Nieuw Amsterdam
Your Route
Jacuzzi
Day 16: St. John's, Antigua
Spa
Day 7: Cartagena, Colombia
Gym

Alternate Sailings

The Nieuw Amsterdam sails this route two times next year, but doesn't sail it this year. No other ship sails this exact same route. In the accompanying graphic you can see a visualization of when this ship sails as well as the relative price.

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec
2026
2027
2028
$2,644 $2,829
Sold Out

See every departure of this route →


Book Your Cruise

Since it was first listed on April 7th of last year, The cost of a stateroom on this sailing has ranged between $2,226 and $3,839 including taxes and port charges. This graph indicates the cost over time for the different types of cabin. Now this itinerary is just nineteen percent more than the all time low of $2,226 so reserve your stateroom now before it goes up.

inside
outside
balcony
suite
$2,644
$3,054
$4,854
$7,464
$125.90/day
$145.43/day
$231.14/day
$355.43/day
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Last Updated: Sep 23, 2026

Last Modified: Sep 17, 2026

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