Santiago is not itself a cruise port, but is served by the ports of Valparaiso and Valparaiso. In total, Valparaiso and Valparaiso is the point of embarkation for one cruises yearly from Celebrity to South America and Latin America.
On average Santiago is fairly expensive compared to other ports. The graph below shows the monthly average cost per day for cruises from Santiago (Cruises only depart from Santiago between January and December). Cruises departing from Santiago during the the peak season of winter are somewhat more expensive than the the low season of spring.