Holland America Rotterdam 21-Night Rome to Istanbul
Holland America Rotterdam (Holland America) sails this 21-night route from Rome to Istanbul on 1 upcoming date (Nov 2028), from $2,904 per person. Every departure below links to its own page with live cabin prices, the full itinerary and online booking.
Ports on this route
Civitavecchia → Naples → Messina → Kotor → Split → Zadar → Trieste → Dubrovnik → Kotor → Corfu → Piraeus → Santorini → Mykonos → Kuşadası → Thessaloniki → Istanbul
All upcoming departures
November 11, 2028
21 Night European Cruise from Rome to Istanbul
CruiseScore™ (4.53/5)
Holland America Rotterdam
S
M
L
XL
Rome
→
Naples
→
Messina
→
Kotor
→
Split
→
Zadar
→
Trieste
→
Dubrovnik
→
Kotor
→
Corfu
→
Athens
→
Santorini
→
Mykonos
→
Ephesus
→
Thessaloniki
→
Istanbul
Inside
Inside
