21 Night from Rome to Istanbul on the Holland America Rotterdam
Join the Holland America Rotterdam and prepare yourself for twenty-one nights of leisurely cruising on the Mediterranean from Rome to Istanbul!
With this Thanksgiving sailing you'll stop at favorite cities such as Piraeus and Naples as well as extremely rare cities such as Thessaloniki and Trieste. This route is an interesting one for the Rotterdam. As a matter of fact, it sails it only once.
We include all all taxes and fees in our price, so that you can compare trips easily. With a cost of less than $140 per day, this represents a good deal.
The Holland America Rotterdam
Over 2,600 travelers can comfortably cruise on this highly-rated Pinnacle class ship, based in Rotterdam and Fort Lauderdale and built only five years ago in 2021.
The Rotterdam Holland America is home to.
Your Itinerary
This itinerary includes five sea days and fifteen port days. High points include visits to very uncommon stops like Thessaloniki and Trieste in addition to long stops in Dubrovnik and Kuşadası.
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Outlook
Alternate Sailings
No other ship sails this exact same route. In the accompanying graphic you can see a visualization of when this ship sails as well as the relative price.
Book Your Cruise
The accompanying graph indicates the cost over time for each class of cabin. Since being listed a couple months ago, The cost of a stateroom on this itinerary has fluctuated between $2,904 and $2,909 inclusive of taxes and port fees. Right now this cruise is only $5 more than the all time low of $2,904 so reserve your stateroom now before it goes up.
Last Updated: Oct 7, 2026
Last Modified: Sep 17, 2026