12 Night from Santiago to Panama City on the Crystal Serenity
Join the Crystal Serenity and get ready for twelve nights of refreshing sailing through the sea from Santiago to Panama City!
This sailing is particularly interesting because you'll exclusively tour through rare stops like Guayaquil, Iquique, and Salaverry. This route is an unusual one for the Serenity. Actually, it sails it just once.
The price is the total you pay for an outside cabin, no sneaky extra fees.
The Crystal Serenity
Over 700 passengers can comfortably travel on the flagship of the class, based in Europe and refurbished only this year ago in 2026.
The Serenity Crystal is home to a jacuzzi, a gym, a spa, a casino, and a ping pong table.
Your Itinerary
This itinerary spends four sea days and seven port days. Major features include long stops in Lima and Guayaquil as well as visits to very uncommon cities like Iquique and Salaverry.
| Date | Port | Arrive | Depart |
|---|---|---|---|
| Mon, Nov 29 | Valparaiso, Chile (Santiago) | 7:00pm | |
| Tue, Nov 30 | Coquimbo, Chile | 9:00am | 6:00pm |
| Wed, Dec 1 | At Sea | ||
| Thu, Dec 2 | Iquique, Chile | 8:00am | 6:00pm |
| Fri, Dec 3 | At Sea | ||
| Sat, Dec 4 | Pisco, Peru | 8:00am | 6:00pm |
| Sun, Dec 5 | Lima, Peru | 7:00am | 7:00pm |
| Mon, Dec 6 | Salaverry, Peru | 11:00am | 8:00pm |
| Tue, Dec 7 | At Sea | ||
| Wed, Dec 8 | Guayaquil, Ecuador | 7:00am | 7:00pm |
| Thu, Dec 9 | At Sea | ||
| Fri, Dec 10 | Fuerte Amador, Panama (Panama City) | 5:00pm | |
| Sat, Dec 11 |
Alternate Sailings
The Serenity sails this route once next year, but doesn't sail it this year. No other ship sails this exact same route. In the accompanying graphic you can see a visualization of when this ship sails as well as the relative price for an outside cabin.
Book Your Cruise
This graph shows the price over time for each type of cabin. Since it was first listed on July 17th of this year, the price of this cruise has remained steady at $5,920 for an outside cabin. Right now this itinerary is at its lowest price, so reserve your outside room now before it moves upwards.
Last Updated: Jul 18, 2026
Last Modified: Jul 17, 2026