23 Night from Santiago to Fort Lauderdale on the Crystal Serenity

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Settle in for twenty-three nights of refreshing sailing across the sea when you step aboard the Crystal Serenity from Santiago to Fort Lauderdale.

This cruise is special because you'll only call on very uncommon stops such as Iquique, Guayaquil, and Salaverry. This route is a special one for the Serenity, As it sails it just once.

This price is the total price for an outside cabin, including meals, entertainment, taxes, and fees. What makes this cruise special is that if you book now you can book a window outside cabin for the interior price!


The Crystal Serenity

The Serenity Crystal, based in and refurbished only this year ago in 2026, is the highly-rated namesake of Crystal's Serenity class and can accomodate comfortably over 700 travelers.

The Serenity Crystal is home to a gym, a casino, a ping pong table, a jacuzzi, and a spa.

Ship class
Serenity
Built
2003
Refurbished
2026
Guests
740
Crew
655
Length
820 ft
Crystal Serenity
Bars & cafésAvenue Saloon

Your Itinerary

This sailing is made up of seven sea days and fifteen days in port. Highlights include visits to rare destinations like Iquique and Salaverry plus long stops in Callao and Guayaquil.

Map of this cruise's route
© OpenStreetMap · © ESA WorldCover
Mon29November 29thMonday
7:00pm
Tue30November 30thTuesday
9:00am – 6:00pm
9:00am – 6:00pm
Wed1December 1stWednesday
At Sea
Thu2December 2ndThursday
8:00am – 6:00pm
8:00am – 6:00pm
Fri3December 3rdFriday
At Sea
Sat4December 4thSaturday
8:00am – 6:00pm
8:00am – 6:00pm
Sun5December 5thSunday
7:00am – 7:00pm
Mon6December 6thMonday
11:00am – 8:00pm
11:00am – 8:00pm
Tue7December 7thTuesday
At Sea
Wed8December 8thWednesday
7:00am – 7:00pm
Thu9December 9thThursday
At Sea
Fri10December 10thFridaySat11December 11thSaturday
5:00pm – 5:00pm5:00pm – 5:00pm
Sun12December 12thSunday
Panama Canal (Cruising)
Mon13December 13thMonday
8:00am – 6:00pm
Tue14December 14thTuesday
At Sea
Wed15December 15thWednesday
8:00am – 6:00pm
8:00am – 6:00pm
Thu16December 16thThursday
8:00am – 6:00pm
Fri17December 17thFriday
8:00am – 6:00pm
Sat18December 18thSaturdaySun19December 19thSunday
9:00am – 5:00pm
9:00am – 5:00pm9:00am – 5:00pm
Mon20December 20thMonday
8:00am – 6:00pm
Tue21December 21stTuesday
At Sea
Wed22December 22ndWednesday
7:00am
Day 2Coquimbo
Day 6Pisco
Day 7Lima
Day 10Guayaquil
Day 15Puerto Limon
Day 17Roatan

Book Your Cruise

Since being listed a few months ago, The price of this cruise has ranged between $10,100 and $10,700 for an outside room, inclusive of taxes and port charges. Now this cruise is just $600 more expensive than the all time low of $10,100 so lock in your outside cabin now before it goes up.

Photos show a typical cabin in each class. Layout and decor vary by category.


Resources

Add it to your calendar

Your departure and return dates in the calendar you already use.

Add every port stop to Google Calendar

Printable CruiseSheet

One page with the route, the day-by-day schedule, typical weather and a notes box for each day.

Stay connected on board

A GigSky eSIM works on the ship and ashore in the Americas and the Caribbean, so your phone just works without the ship's Wi‑Fi package.

Unlimited data for your 24 days $283.49 $240.97

500 MB a day at full speed, then 500 kbps; messaging, email and maps apps stay unlimited.

More plans at GigSky


Alternate Sailings

The Serenity sails this route once next year, but doesn't sail it this year. No other ship sails this exact same route.

No other departures of this route are on sale right now.

Show alternate dates for this cruise → Show all cruises that sail this route →

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Data as of Oct 24, 2026

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Guests in this cabin
Ages at the time of sailing

Special fares are dependent on eligibility

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