21 Night Panama Canal Cruise aboard the Holland America Nieuw Amsterdam

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Set sail with the Holland America Nieuw Amsterdam and settle in for twenty-one nights of breathtaking travel across the sea from Vancouver to Fort Lauderdale!

Spending time at rare ports such as Acajutla, Puerto Chiapas, and Huatulco makes this cruise special. This route is an uncommon one for the Nieuw Amsterdam, As it sails it only once.

This price just dropped, so book today to reserve your cabin before the price moves upwards again! This includes all entertainment, meals, port fees, and taxes. No surprises! Offered at less than $115 per day, this deal is very strong.

Spa
Day 6: San Diego

The Holland America Nieuw Amsterdam

More than 2,100 people can comfortably sail on this top-rated Signature class vessel, based in Fort Lauderdale and refurbished just three years ago in 2023.

The Nieuw Amsterdam Holland America offers a spa, a gym, a casino, and seven jacuzzis.

Holland America Nieuw Amsterdam
Day 18: Cartagena, Colombia

Your Itinerary

This itinerary spends nine days in port and eleven sea days. Highlights include visits to once-in-a-lifetime ports like Acajutla, Puerto Chiapas, and Huatulco plus long stops in San Francisco and Puerto Quetzal.

Sun27September 27thSunday
4:00pm
Mon28September 28thMonday
At Sea
Tue29September 29thTuesday
At Sea
Wed30September 30thWednesday
7:00am – 9:00pm
7:00am – 9:00pm
Thu1October 1stThursday
At Sea
Fri2October 2ndFriday
7:00am – 4:00pm
7:00am – 4:00pm
Sat3October 3rdSaturday
At Sea
Sun4October 4thSunday
At Sea
Mon5October 5thMonday
8:00am – 5:00pm
Tue6October 6thTuesday
At Sea
Wed7October 7thWednesday
10:00am – 5:00pm
10:00am – 5:00pm
Thu8October 8thThursday
8:00am – 5:00pm
Fri9October 9thFriday
6:00am – 8:00pm
Sat10October 10thSaturday
7:00am – 5:00pm
Sun11October 11thSunday
At Sea
Mon12October 12thMonday
At Sea
Tue13October 13thTuesday
Panama Canal (Cruising)
Wed14October 14thWednesday
12:00pm – 6:00pm
12:00pm – 6:00pm
Thu15October 15thThursday
At Sea
Fri16October 16thFriday
At Sea
Sat17October 17thSaturday
8:00am – 2:00pm
Sun18October 18thSunday
7:00am
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Print your CruiseSheet (PDF) one page with the route, schedule, weather & a notes box for each day
September 27th, 2026  - Panama Canal Cruise on the Holland America Nieuw Amsterdam
Your Route
Day 9: Puerto Vallarta
Gym
Jacuzzi
Day 4: San Francisco
Day 11: Huatulco

Alternate Sailings

The Nieuw Amsterdam sails this route once this year. This is the only ship that sails this exact route. In the accompanying graphic you can see a visualization of when this ship sails as well as the relative price.

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec
2026
2027
2028
$2,339 $2,339
Sold Out

See every departure of this route →


Book Your Cruise

Since it was first listed on April 7th of last year, The price of a room on this itinerary has varied between $1,833 and $3,360 including taxes and port fees. The accompanying graph displays the cost over time for the various types of cabin.

inside
outside
balcony
suite
$2,339
$2,419
$2,624
$20,499
$111.38/day
$115.19/day
$124.95/day
$976.14/day
Book Book Book Book

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Last Updated: Aug 14, 2026

Last Modified: Aug 10, 2026

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