7 Night Greek Isles & Italy Cruise aboard the Royal Caribbean Odyssey of the Seas
Prepare for seven nights of luxurious travel on the Mediterranean when you join the Royal Caribbean Odyssey of the Seas from Rome and back again.
While aboard this cruise you'll tour through usual stops like Naples in addition to unusual stops like Santorini, Mykonos, and Messina. This route is a special one for the Odyssey of the Seas.
We include all meals, entertainment, port charges, and taxes in our price, so there are no surprises.
The Royal Caribbean Odyssey of the Seas
More than 3,800 guests can comfortably sail on this highly-rated Quantum Ultra class vessel, based in Bayonne and Rome and refurbished less than this year ago in 2026.
The Odyssey of the Seas Royal Caribbean is home to a selection of Royal Caribbean's exclusive activities such as a bar with a robotic bartender, the Flowrider artificial surf wave, and an indoor skydiving chamber. Want more? Experience rare amenities like a bumper car track, a trampoline park, and a roller skating rink.
The Odyssey of the Seas Royal Caribbean also offers a waterslide, a basketball court, a gym, a spa, a jacuzzi, a casino, a solarium, and an outdoor movie theater.
Your Itinerary
This cruise is made up of two days at sea and four days in port. High points include long stops in Messina, Santorini, and Naples plus visits to unusual ports like Mykonos.
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Outlook
Alternate Sailings
The Odyssey of the Seas sails this route two times this year. No other ship sails this exact same route. In the accompanying graphic you can see a visualization of when this ship sails as well as the relative price for a balcony cabin.
Book Your Cruise
Since it was first listed on November 21st of last year, The cost of this itinerary has ranged between $1,268 and $3,683 for a balcony stateroom, including taxes and port fees. This graph shows the cost over time for the different types of cabin.
Last Updated: Oct 4, 2026
Last Modified: Oct 4, 2026