7 Night Greek Isles & Italy Cruise aboard the Royal Caribbean Odyssey of the Seas

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Get ready for seven nights of refreshing sailing through the sea when you embark on the Royal Caribbean Odyssey of the Seas from Rome and back.

During this cruise you will spend time at favorite ports like Naples in addition to unusual ports like Santorini, Mykonos, and Messina. This route is an interesting one for the Odyssey of the Seas, But October is the most popular time of year to sail it.

Book now, because the price of this itinerary is going up! Reserve your room before the price moves upwards. This is the total you pay, no surprises.

Day 5: Mykonos
Day 2: Messina

The Royal Caribbean Odyssey of the Seas

Based in Bayonne and Rome and built just five years ago in 2021, more than 3,800 guests can sail on this top-rated Quantum Ultra class ship.

The Odyssey of the Seas Royal Caribbean offers guests several of Royal Caribbean's exclusive activities such as the Flowrider artificial surf wave, an indoor skydiving chamber, and a bar with a robotic bartender. Plus, experience rare features like a roller skating rink, a trampoline park, and a bumper car track.

The Odyssey of the Seas Royal Caribbean also offers a solarium, a spa, a basketball court, an outdoor movie theater, a casino, a gym, a jacuzzi, and a waterslide.

Royal Caribbean Odyssey of the Seas
Bar With A Robotic Bartender

Your Itinerary

This itinerary includes four port days and two days at sea. Major features include visits to more exotic ports like Mykonos as well as long stops in Messina, Santorini, and Naples.

DatePortArriveDepart
Sun, Oct 18Civitavecchia, Italy (Rome)4:00pm
Mon, Oct 19Messina, Sicily 10:00am9:00pm
Tue, Oct 20At Sea
Wed, Oct 21Santorini, Greece 7:00am10:00pm
Thu, Oct 22Mykonos, Greece 7:00am5:00pm
Fri, Oct 23At Sea
Sat, Oct 24Naples, Italy 7:00am6:00pm
Sun, Oct 25Civitavecchia, Italy (Rome)5:00am
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Print your CruiseSheet (PDF) one page with the route, schedule, weather & a notes box for each day
October 18th, 2026  - Greek Isles & Italy Cruise on the Royal Caribbean Odyssey of the Seas
Your Route
Indoor Skydiving Chamber
Day 4: Santorini
Bumper Car Track

Alternate Sailings

The Odyssey of the Seas sails this route two times this year. No other ship sails this exact same route. In the accompanying graphic you can see a visualization of when this ship sails as well as the relative price.

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec
2026
2027
2028
$1,279 $1,378
Sold Out

See every departure of this route →


Book Your Cruise

Since being listed twenty months ago, The price of this itinerary has fluctuated between $1,210 and $2,003 for a room, including taxes and port fees. This graph shows the cost over time for the various types of cabin. Today this sailing is just $168 higher than the all time low of $1,210 so reserve your cabin now before it goes up.

inside
outside
balcony
suite
$1,378
$1,618
$1,680
$2,640
$196.86/day
$231.14/day
$240.00/day
$377.14/day
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Last Updated: Jul 17, 2026

Last Modified: Jul 15, 2026

Continue Booking from $1,378 Continue Booking